Acute non-lymphocytic leukemia after treatment with dacarbazine in combination with other cytotoxic drugs has been reported in a patient with breast cancer and after adjuvant treatment with single-agent dacarbazine in a patient with melanoma (13 A).
Dacarbazine has been associated with leukemias in some reports. Therefore Dacarbazine medac is contraindicated during pregnancy (see section 4.3 and 4.4.). Common side effects may include: loss of appetite; diarrhea; temporary hair loss; mild skin rash; or numbness, warmth, redness, or tingly feeling in your face.
Call your doctor for medical advice about side effects. Acute non-lymphocytic leukemia after treatment with dacarbazine in combination with other cytotoxic drugs has been reported in a patient with breast cancer and after adjuvant treatment with single-agent dacarbazine in a patient with melanoma (13 A). Other serious side effects include liver problems and allergic reactions. Tumorigenicity. Dacarbazine This treatment can have serious or possibly life-threatening side effects. Ami Sabharwal, Mark Middleton, in Side Effects of Drugs Annual, 2010.
You will have treatment every 3 weeks for up to 6 cycles.
Dacarbazine can lower blood cells that help your body fight infections and help your blood to clot. Continue your course of treatment even though you feel ill unless your doctor tells you to stop. Your doctor will monitor you closely while you are receiving this medication. Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets. Increased risk of getting an infection.
Women of child-bearing potential have to use effective contraception during treatment.
Dacarbazine is sometimes given daily for 5 to 10 days in a row every 3 or 4 weeks. Your doctor will determine how long to treat you with dacarbazine. It is given by injection into a vein.. Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets. Day 1 Dacarbazine is given as a intravenous infusion (drip) which lasts . Dacarbazine may also cause rare but serious liver problems.
Dacarbazine is in the alkylating agent and purine analog families of medication.. Dacarbazine was approved for medical use in the United States in 1975. Do not treat yourself. Important things to remember about the side effects of Dacarbazine (Table-2) : Table 2 - Side Effects. Dacarbazine for Injection BP: Dacarbazine belongs to the group of cancer-fighting medications called antineoplastics. For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin. Common side effects may include: loss of appetite; diarrhea; temporary hair loss; mild skin rash; or numbness, warmth, redness, or tingly feeling in your face. This medication slows the growth and spread of cancer cells in the body. Ami Sabharwal, Mark Middleton, in Side Effects of Drugs Annual, 2010. It kills cancer cells by interfering with their growth and reproduction. Dacarbazine is used to treat skin cancer (malignant melanoma) and Hodgkin's disease. This is not a complete list of side effects and others may occur. What is the most important information I should know about dacarbazine? Efficacy and side effects of dacarbazine in comparison with temozolomide in the treatment of malignant melanoma: a meta-analysis consisting of 1314 patients.
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